4-HO-EiBT

4-HO-EiBT
Clinical data
Other names4-Hydroxy-N-ethyl-N-isobutyltryptamine; Eibucin
Drug classSerotonin receptor modulator; Serotonin 5-HT2A receptor agonist
Identifiers
IUPAC name
  • 3-{2-[(2-methylpropyl)(ethyl)amino]ethyl}-1H-indol-4-ol
CAS Number
PubChem CID
Chemical and physical data
FormulaC16H24N2O
Molar mass260.381 g·mol−1
3D model (JSmol)
SMILES
  • CCN(CCc1c[nH]c2cccc(O)c12)CC(C)C
InChI
  • InChI=1S/C16H24N2O/c1-4-18(11-12(2)3)9-8-13-10-17-14-6-5-7-15(19)16(13)14/h5-7,10,12,17,19H,4,8-9,11H2,1-3H3
  • Key:ASUXKVXXFBPGCG-UHFFFAOYSA-N

4-HO-EiBT, also known as 4-hydroxy-N-ethyl-N-isobutyltryptamine or as eibucin, is a substituted tryptamine derivative which acts as a serotonin 5-HT2A receptor agonist, with an EC50Tooltip half-maximal effective concentration of 27.7 nM and an efficacy of 97.5%.[1]

Chemistry

Analogues

Analogues of 4-HO-EiBT include 4-HO-DiPT, 4-HO-DsBT, 4-HO-McPT, 4-HO-McPeT, 4-HO-MiPT, and 4-HO-PiPT, among others.

See also

References

  1. ↑ WO 2023/115167, Banister S, Jorgensen W, Jinlong T, "Compounds", published 2023-06-29, assigned to Psylo Pty Ltd.. Retrieved 2025-05-12
This article is issued from WikiProjectMed. The text is available under Creative Commons Attribution-ShareAlike License unless otherwise noted. Additional terms may apply for the media files.