Mannosulfan

Mannosulfan
Clinical data
Other names[(2R,3S,4S,5R)-3,4-dihydroxy-2,5,6-tris(methylsulfonyloxy)hexyl] methanesulfonate
ATC code
Identifiers
IUPAC name
  • 1,2,5,6-Tetrakis-O-(methylsulfonyl)-D-mannitol
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC10H22O14S4
Molar mass494.51 g·mol−1
3D model (JSmol)
SMILES
  • CS(=O)(=O)OC[C@H]([C@H]([C@@H]([C@@H](COS(=O)(=O)C)OS(=O)(=O)C)O)O)OS(=O)(=O)C
InChI
  • InChI=1S/C10H22O14S4/c1-25(13,14)21-5-7(23-27(3,17)18)9(11)10(12)8(24-28(4,19)20)6-22-26(2,15)16/h7-12H,5-6H2,1-4H3/t7-,8-,9-,10-/m1/s1
  • Key:UUVIQYKKKBJYJT-ZYUZMQFOSA-N
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Mannosulfan (INN) is an alkylating agent with the potential for the treatment of cancer. It is not approved by the United States FDA for cancer treatment. Research suggests it is less toxic than the alkyl sulfonate Busulfan.[1]

References

  1. ↑ Jeswani G, Paul SD (2017). "Recent Advances in the Delivery of Chemotherapeutic Agents". Nano- and Microscale Drug Delivery Systems. pp. 281–98. doi:10.1016/B978-0-323-52727-9.00015-7. ISBN 978-0-323-52727-9.


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