Clichy criteria

The Clichy criteria, also called the Beaujon-Paul Brousse criteria,[1] are a group of criteria proposed to predict the survival of individuals with acute liver failure. It was based on a study of patients presenting with viral hepatitis, of which individuals with the lowest survival were identified. The King's College Criteria are more commonly used.[2] Other prognostic models include Acute Liver Failure Early Dynamic (ALFED) model, Model for End-Stage Liver Disease (MELD) score, and the Acute Liver Failure Study Group (ALFSG) Index.[1]

Two criteria predicted the prognosis of patients with poor survival:

  • Factor V level less than 20 percent of its normal value in individuals less than thirty years of age
  • Factor V level less than 30 percent of its normal value in individuals greater than thirty years of age.

The positive predictive value of mortality was 82% and the negative predictive value of mortality was 98% in individuals meeting these criteria.

References

  1. 1 2 Singh, Virendra; Roy, Akash (2022-01-29). Clinical Rounds in Hepatology. Springer Nature. p. 12. ISBN 978-981-16-8448-7.
  2. Ferri, Fred F. (2023-06-13). Ferri's Clinical Advisor 2024, E-Book. Elsevier Health Sciences. pp. 62–62.e1. ISBN 978-0-323-75577-1.