1-Aminotetralin

1-Aminotetralin
Names
IUPAC name
1,2,3,4-tetrahydronaphthalen-1-amine
Other names
1-AT; 1-Amino-1,2,3,4-tetrahydronaphthalene
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.017.012
EC Number
  • 220-973-7
PubChem CID
UNII
InChI
  • InChI=1S/C10H13N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10H,3,5,7,11H2
    Key: JRZGPXSSNPTNMA-UHFFFAOYSA-N
SMILES
  • C1CC(C2=CC=CC=C2C1)N
Properties
Chemical formula
 C10H13N
Molar mass 147.221 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

1-Aminotetralin (1-AT), also known as 1-amino-1,2,3,4-tetrahydronaphthalene, is a chemical compound and one of the possible positional isomers of aminotetralin.[1] It consists of a tetralin core with an amino substituent on one of the carbon atoms.

Derivatives

1-Aminotetralin is the parent structure of a number of drugs, including the following:[2]

Tramazoline is another related compound.[2]

See also

  • 2-Aminotetralin
  • Aminoindane

References

  1. ↑ Trachsel, D.; Lehmann, D.; Enzensperger, C. (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. p. 263. ISBN 978-3-03788-700-4. OCLC 858805226.
  2. 1 2 Shah, Bhumi M.; Kachhadiya, Radhika N. (2025). "Shaping the future of medicine through diverse therapeutic applications of tetralin derivatives". Medicinal Chemistry Research. 34 (1): 86–113. doi:10.1007/s00044-024-03331-y. ISSN 1054-2523.



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